Faculty

Jan, Jeng-Shiung 詹正雄 (Professor)

Contact：

Office：93815
Phone：(06)-2757575-62660
Fax：(06)-2344496
E-mail：jsjan@mail.ncku.edu.tw
Website：http://jjslab.weebly.com/
Research Expertise：
Functional Polymeric Materials, Bionanomaterials, Biomimetic or Bio-inspired Materials, Drug/Protein Delivery


NCKU Research: https://researchoutput.ncku.edu.tw/en/persons/jeng-shiung-jan

Personal CV ：

Education

Ph.D., Chemical Engineering
Texas A&M University, College Station, TX Dec 2006

M.S., Chemical Engineering
Biomedical Engineering Certificate
National Taiwan University, Taipei, Taiwan June 1996

B.S., Chemical Engineering,
National Taiwan University, Taipei, Taiwan June 1994

Experience

Professor, National Cheng Kung University (Aug 2016 - present)

Associate Professor, National Cheng Kung University (Aug 2012 - July 2016)

Assistant Professor, National Cheng Kung University (Feb 2009 - July 2012)

Research Assistant Professor, National Cheng Kung University (Aug 2008 - Jan 2009)

Postdoctoral fellow, Georgia Institute of Technology (Feb 2007- Aug 2008)

Teaching

Unit Operation I

Engineering Mathematics II

Special Topics on Biomaterials

Introduction to Transport in Microfluidic Devices

 

Publications

Publications

  1. Tseng,Y.-C.; Wu. Y.; Tsao, C.-H.; Teng, H.; Hou, S.-S.*; Jan, J.-S.* "Polymer Electrolytes Based on Poly(VdF-co-HFP)/Ionic Liquid/Carbonate Membranes for High-Performance Lithium-Ion Batteries" Polymer, 2019, 173, 110-118. (Polymer science，Ranking: 14/87 = 16.1％, IF:3.483)

  2. Chen, K.-J.; Chen, H.-L.; Tang, C.-C.; Wu, H.-H.; Jan, J.-S.* "Synthesis of Silica/Polypeptide Hybrid Nanomaterials and Mesoporous Silica by Molecular Replication of Sheet-Like Polypeptide Complexes through Biomimetic Mineralization" J. Colloid Interface Sci., 2019, 542, 243−252. (Chemistry, physical, Ranking: 33/147 = 22.4％, IF:5.091)
  3. Hou, S.-S.; Fan, N.-S.; Tseng, Y.-C.; Jan, J.-S.* "Self-Assembly and Hydrogelation of Coil-Sheet Poly(L-Lysine)-block-Poly(L-Threonine) Block Copolypeptides" Macromolecules, 2018, 51, 8054−8063. (Polymer science，Ranking: 5/87 = 5.7％, IF:5.914)
  4. Chen, Y.-F.; Chang, C.-H.; Huang, Z.-N.; Su, Y.-C.; Chang, S.-J.*; Jan, J.-S.* " The JAK Inhibitor Antcin H Exhibits Direct Anti-Cancer Activity while Enhancing Chemotherapy against LMP1-Expressed Lymphoma" Leuk. Lymph., 2018, doi: 10.1080/10428194.2018.1512709. (Hematology，Ranking: 34/71 = 47.9％, IF:2.644)
  5. Shen, X.-Y.; Tang, C.-C.; Jan, J.-S.* "Synthesis and Hydrogelation of Star-Shaped Poly(L-lysine) Polypeptides Modified with Different Functional Groups" Polymer, 2018, 151, 108-116. (Polymer science，Ranking: 14/87 = 16.1％, IF:3.483)
  6. Tsai, Y.-L.; Tseng,Y.-C.; Chen, Y.-M.; Wen, T.-C.; Jan, J.-S.* "Zwitterionic Polypeptides Bearing Carboxybetaine and Sulfobetaine: Synthesis, Self-Assembly, and Their Interactions with Proteins"Polym. Chem., 2018, 9, 1178–1189. (Polymer science，Ranking: 8/87 = 9.2％, IF:4.927)
  7. Chen, Y.-F.; Chang, C.-H.; Lin, C.-Y.; Lin, L.-F.; Yeh, M.-L.*; Jan, J.-S.* "Disulfide-Cross-Linked PEG-block-Polypeptide Nanoparticles with High Drug Loading Content as Glutathione-Triggered Anticancer Drug Nanocarriers" Colloid Surf. B: Biointerfaces, 2018, 165, 172–181. (Chemistry, physical, Ranking: 44/146 = 30.1％, IF:3.997)
  8. Chen, Y.-M.; Hsu, S.-T.; Tseng, Y.-H.; Yeh, T.-F.; Hou, S.-S.; Jan, J.-S.; Lee, Y.-L.; Teng, H.* "Minimization of Ion–Solvent Clusters in Gel Electrolytes Containing Graphene Oxide Quantum Dots for Lithium-Ion Batteries" Small, 2018, 1703571. (Materials science, multidisciplinary, Ranking: 22/285 = 7.7％, IF:9.598)
  9. Lin, T.-X.; Chen, K.-J.; Chen, P.-Y.; Jan, J.-S.* "Broadband Antireflection Coatings Based on Low Surface Energy/ Refractive Index Silica/Fluorinated Polymer Nanocomposites" ACS Appl. Nano Mater., 2018, 1, 741−750. (Materials science, multidisciplinary, Ranking: 26/285 = 9.17％, IF:8.097)
  10. Chen, Y.-F.; Shiau, A.-L.; Chang, S.-J.; Fan, N.-S.; Wang, C.-T.; Wu, C.-L.*; Jan, J.-S.* "One-Dimensional Poly(L-lysine)-block-Poly(L-threonine) Assemblies Exhibit Potent Anticancer Activity by Enhancing Membranolysis" Acta Biomater. 2017, 55, 283–295. (Engineering, biomaterials, Ranking: 3/72 = 4.2％, IF:6.319)
  11. Lin, Y.-Y.; Chen, Y.-M.; Hou, S.-S.; Jan, J.-S.; Lee, Y.-L.; Teng, H.-S. "Diode-like Gel Polymer Electrolytes for Full-Cell Lithium Ion Batteries" J. Mater. Chem. A 2017, 5, 17476–17481. (Materials science, multidisciplinary, Ranking: 20/275 = 7.3％, IF:8.867)
  12. Hsiao, L.-W.; Lai, Y.-D.; Lai, J.-T.; Hsu, C.-C.; Wang, N.-Y.; Wang, S. S.-S.; Jan, J.-S.* " Cross-Linked Polypeptide-Based Gel Particles by Emulsion for Efficient Protein Encapsulation" Polymer 2017, 115, 261–272. (Polymer science，Ranking: 11/86 = 11.6％, IF:3.684)
  13. How, S.-C.; Chen, Y.-F.; Hsieh, P.-L.; Wang, S. S.-S.*; Jan, J.-S.* "Cell-Targeted, Dual Reduction- and pH-responsive Saccharide/Lipoic Acid-Modified Poly(L-lysine) and Poly(acrylic acid) Polyionic Complex Nanogels for Drug Delivery"Colloid & Surface B: Biointerfaces 2017, 153, 244–252. (Chemistry, physical, Ranking: 39/144 = 27.1％, IF:3.902)
  14. Lee, P.-Y.; Tuan-Mu, H.-Y.; Hsiao, L.-W.; Hu, J.-J.*; Jan, J.-S.* "Nanogels Comprising Reduction-cleavable Polymers for Glutathione-Induced Intracellular Curcumin Delivery" J. Polym. Res. 2017, 24, 66. (Polymer science, Ranking: 31/85 = 36.5％, IF:1.969)
  15. Hou, S.-S.; Hsu, Y.-Y.; Lin, J.-H.; Jan, J.-S.* "Alkyl-poly(L‑threonine)/Cyclodextrin Supramolecular Hydrogels with Different Molecular Assemblies and Gel Properties"ACS Macro Lett. 2016, 5, 1201–1205. (Polymer science, Ranking: 3/85 = 3.5％, IF:5.766)
  16. Lin, T.-X.; Hsu, F.-M.;Lee, Y.-L.;Goseki, R.;Ishizone, T.;Jan, J.-S.* "Synthesis of Antireflective Silica Coatings through the Synergy of Polypeptide Layer-by-Layer Assemblies and Biomineralization"ACS Appl. Mater. Interfaces 2016, 8, 26309–26318. (Materials science, multidisciplinary, Ranking: 25/271 = 9.2％, IF:7.145)
  17. Lee, Y.-L.; Lin, T.-X.; Hsu, F.-M.; Jan, J.-S.* "Synthesis of Antireflective Silica Coatings through the Synergy of Polypeptide Layer-by-Layer Assemblies and Biomineralization" Nanoscale 2016, 8, 2367–2377. (Materials science, multidisciplinary, Ranking: 23/271 = 8.5％, IF:7.76)
  18. Zhang, Y.-X.; Chen, Y.-F.; Shen, X.-Y.; Jan, J.-S.* "Redox- and pH-Sensitive Lipoic Acid-Modified Poly(L-lysine) and Polypeptide/Silica Hybrid Hydrogels/Nanogels" Polymer 2016, 86, 32–41. (Polymer science，Ranking: 12/85 = 14.1％, IF:3.586)
  19. Lee, M.-H.; Thomas, J. L.; Chen, J.-Z.; Jan, J.-S.; Lin, H.-Y. "Activation of Tumor Suppressor p53 Gene Expression by Magnetic Thymine-imprinted Chitosan Nanoparticles" Chem. Commun. 2016, 52, 2137–2140.(Chemistry, multidisciplinary, Ranking: 21/163 = 12.9％, IF:6.567)
  20. Liu, S.-T.; Tuan-Mu, H.-Y.; Hu, J.-J.; Jan, J.-S.* "Genipin cross-linked PEG-block-poly(L-lysine)/disulfide-based polymer complex micelles as fluorescent probes and pH-/redox-responsive drug vehicles" RSC Adv. 2015, 5, 87098–87107.(Chemistry, multidisciplinary, Ranking: 49/163 = 30.1％, IF:3.289)
  21. Wang, S. S.-S.; How, S.-C.; Chen, Y.-D.; Tsai, Y.-H.; Jan, J.-S.* "Bioactive Saccharide-Conjugated Polypeptide Micelles for Acid-Triggered Doxorubicin Delivery" J. Mater. Chem. B 2015, 3, 5220-5231. (Materials science, biomaterials，Ranking: 7/33 = 21.2％, IF:4.726)
  22. Lee, M.-H.; Thomas, J. L.; Li, M.-H.; Shih, C.-P.; Jan, J.-S.; Lin, H.-Y. "Recognition of Rhodobacter sphaeroides by microcontact-imprinted poly(ethylene-co-vinyl alcohol)" Colloid & Surface B: Biointerfaces 2015, 135, 394-399. (Chemistry, physical，Ranking: 34/139 = 24.5％, IF:4.152)
  23. Chen, B.-Y.; Huang, Y.-C.; Jan, J.-S.* "Molecular Assembly of Alkyl Chain-Grafted Poly(L-lysine) Tuned by Backbone Chain Length and Grafted Alkyl Chain" RSC Adv. 2015, 5, 22783-22791. (Chemistry, multidisciplinary，Ranking: 35/148 = 23.6％, IF:3.708)
  24. Hu, J.-J.; Hsieh, Y.-H.; Jan, J.-S.* "Polyelectrolyte Complex-Silica Hybrid Colloidal Particles Decorated with Different Polyelectrolytes" J. Colloid Interface Sci. 2015, 438, 94-101. (Chemistry, physical，Ranking: 38/136 = 27.9％, IF:3.552)
  25. Hsieh, Y.-H.; Hsiao, Y.-T.; Jan, J.-S.* "Shell and Core Cross-Linked Poly(L-lysine)/Poly(acrylic acid) Complex Micelles" Soft Matter 2014, 10, 9568-9576. (Polymer science，Ranking: 9/82 = 11.0％, IF:4.152)
  26. Huang, C.-H.; Li, Y.-C.; Yeh, Y.-Q.; Jeng, U.-S.; Wei, H.-H.*; Jan, J.-S.* "Probing Conformational Transitions of Polymer Chains by Microrheology" Polymer 2014, 55, 3168-3177. (Polymer science，Ranking: 12/82 = 14.6％, IF:3.766)
  27. Huang, Y.-F.; Lu, S.-C.; Huang, Y.-C.; Jan, J.-S.* " Cross-Linked, Self-Fluorescent Gold Nanoparticle/Polypeptide Nanocapsules Comprising Dityrosine for Protein Encapsulation and Label-free Imaging" Small 2014, 10, 1939-1944. (Materials science, multidisciplinary，Ranking: 17/251 = 6.8％, IF:7.514)
  28. Chen, B.-Y.; Huang, Y.-F.; Huang, Y.-C.; Wen, T.-C.; Jan, J.-S.* "Alkyl Chain-Grafted Poly(L-lysine) Vesicles with Tunable Molecular Assembly and Membrane Permeability " ACS Macro Lett. 2014, 3, 220-223. (Polymer science，Ranking: 6/82 = 7.3％, IF:5.242)
  29. Huang, Y.-C.; Jan, J.-S.* "Carboxylmethyl Chitosan-graft-poly(γ-benzyl-L-glutamate) Glycopeptides: Synthesis and Particle Formation as Encapsulants" Polymer 2014, 55, 540-549. (Polymer science，Ranking: 12/82 = 14.6％, IF:3.766)
  30. Shiu, C. C.; Wang, S.; Chang, C.-H.;Jan, J.-S.* " Poly(L-glutamic acid)-Decorated Hybrid Colloidal Particles from Complex Particle-Templated Silica Mineralization" J. Phys. Chem. B 2013, 117, 10007-10016. (Chemistry, physical，Ranking: 39/136 = 28.7％, IF:3.377)
  31. Wang, S. S.-S.; Hsieh, P.-L.; Chen, P.-S.; Chen, Y.-T.; Jan, J.-S.* "Genipin-Cross-Linked Poly(L-lysine)-Based Hydrogels: Synthesis, Characterization, and Drug Encapsulation" Colloid Surf. B: Biointerfaces 2013, 111, 423-431. (Biophysics，Ranking: 14/74 = 18.9％, IF:4.287)
  32. Kao, C.-Y.; Lai, J.-K.; Lin, T.-H.; Lin, Y.-J.; Jan, J.-S.*; Wang, S. S.-S.* "Examining the Inhibitory Actions of Copolypeptides Against Amyloid Fibrillogenesis of Bovine Insulin" Biochem. Eng. J. 2013, 78, 181-188. (Engineering: chemical，Ranking: 31/133 = 23.3％, IF:2.368)
  33. Huang, Y. -C.; Arham, M.; Jan, J.-S.* "Bioactive Vesicles from Saccharide- and Hexanoyl-Modified Poly(L-lysine) Copolypeptides and Evaluation of the Cross-linked Vesicles as Carriers of Doxorubicin for Controlled Drug Release" Euro. Polym. J. 2013, 49, 726-737. (Polymer science，Ranking: 16/82 = 19.5％, IF:3.242)
  34. Jan, J.-S.*; Chen, P.-S.; Hsieh, P.-L.; Chen, B.-Y. "Silicification of Genipin-Cross-Linked Polypeptide Hydrogels Toward Biohybrid Materials and Mesoporous Oxides" ACS Appl. Mater. Interfaces 2012, 4, 6865-6874. (Materials science, multidisciplinary，Ranking: 26/241 = 10.8％, IF:5.008)
  35. Liu, K.-N.; Lai, C.-M.; Lee, Y.-T.; Wang, S.-N.; Chen, R. P.-Y.; Jan, J.-S.; Liu, H.-S.; Wang, S. S.-S. "Curcumin's pre-incubation temperature affects its inhibitory potency toward amyloid fibrillation and fibril-induced cytotoxicity of lysozyme" Biochim. Biophys. Acta General Subjects 2012, 1820, 1174-1186. (Biophysics，Ranking: 15/72 = 20.8％, IF:3.848)
  36. Huang, Y.-C.; Yang, Y.-S.; Lai, T.-Y.; Jan, J.-S.* "Lysine-block-Tyrosine Block Copolypeptides: Self-Assembly, Cross-linking, and Conjugation of Targeted Ligand for Drug Encapsulation" Polymer 2012, 53, 913-922. (Polymer science，Ranking: 15/83 = 18.1％, IF:3.379)
  37. Ju, J.-J.; Lu, C.-X.; Jan, J.-S.* "Synthesis of Gold Nanowires and Nanoparticles by Tyrosine Reduction of Chloroaurate" J. Nanosci. Nanotech. 2012, 12, 2802-2809. (Materials science, multidisciplinary，Ranking: 90/231 = 39.0％, IF:1.149)
  38. Wen, W.-S.; Lai, J.-K.; Lin, Y.-J.; Lai, C.-M.; Huang, Y.-C.; Wang, S. S.-S.*; Jan, J.-S.* "Effects of Copolypeptides on Amyloid Fibrillation of Hen Egg-White Lysozyme" Biopolymers, 2012, 97, 107-116. (Biochemistry & molecular biology，Ranking: 139/290 = 47.9％, IF:2.879)
  39. Jan, J.-S.*; Chen, P.-J.; Ho, Y.-H. "Bioassisted Synthesis of Catalytic Gold/Silica Nanotubes Using Layer-by-Layer Assembled Polypeptide Templates" J. Colloid Interface Sci. 2011, 358, 409-415. (Chemistry, physical，Ranking: 42/134 = 31.3％, IF:3.070)
  40. Huang, Y.-C.; Arham, M.; Jan, J.-S.* "Alkyl Chain Grafted Poly(L-lysine): Self-Assembly and Biomedical Application as Carriers" Soft Matter 2011, 7, 3975-3983. (Polymer science，Ranking: 7/78 = 9.0％, IF:4.390)
  41. Jan, J.-S.*; Chuang, T.-H.; Chen, P.-J.; Teng, H. "Layer-by-Layer Polypeptide Macromolecular Assemblies-Mediated Synthesis of Mesoporous Silica and Gold Nanoparticle/Mesoporous Silica Tubular Nanostructures" Langmuir 2011, 27, 2834-2843. (Materials science, multidisciplinary，Ranking: 30/231 = 13.0％, IF:4.186)
  42. Chuang, T.-H.; Lin, S.-T.; Wen, T.-C.; Jan, J.-S.* "Layer-by-Layer Assembled Titinia Tubular Nanostructures at Different Synthesis Conditions" J. Nanosci. Nanotech. 2011, 11, 5247-5257. (Materials science, multidisciplinary，Ranking: 90/231 = 39.0％, IF:1.563)
  43. Jan, J.-S.*; Chen, P.-J.; Ho, Y.-H. "Synthesis of Gold Nanoparticle/Silica Nanostructures" Mater. Sci. Forum 2011, 688, 321-325. (EI)
  44. Lai, J.-K.; Chuang, T.-H.; Jan, J.-S.*; Wang, S. S.-S.* "Efficient and Stable Enzyme Immobilization in a Block Copolypeptide Vesicle-Templated Biomimetic Silica Support" Colloid Surf. B: Biointerfaces 2010, 80, 51-58. (Chemistry, physical，Ranking: 47/127 = 37.0％, IF:2.780)
  45. Wei, H.-H.*; Jan, J.-S. "Self Propulsion and Dispersion of Reactive Colloids Due to Entropic Anisotropy" J. Fluid Mech. 2010, 657, 64-88. (Mechanics，Ranking: 9/133 = 7.0％, IF:2.457)
  46. Gaspard, J.; Silas, J. A.; Shantz, D. F.; Jan, J.-S.* "Supramolecular Assembly of Lysine-b-Glycine Block Copolypeptides at Different Solution Conditions" Supramol. Chem. 2010, 22, 178-185. (Chemistry, multidisciplinary，Ranking: 47/147 = 32.0％, IF:1.940)
  47. Jan, J.-S.; Breedveld, V.* "Microrheological Studies of Polyelectrolyte Collapse and Reexpansion in the Presence of Multivalent Counterions" Macromolecules 2008, 41, 6517-6522. (Polymer science，Ranking: 5/79 = 6.3％, IF:4.407)
  48. Jan, J.-S.; Shantz, D. F.* "Biomimetic Silica Formation: Effect of Block Copolypeptide Chemistry and Solution Conditions on Silica Nanostructure " Adv. Mater. 2007, 19, 2951-2956. (Materials science, multidisplinary，Ranking: 7/225 = 3.1％, IF:8.191)
  49. Jan, J.-S.; Lee, S.; Carr, S. C.; Shantz, D. F.* "Biomimetic Synthesis of Inorganic Nanospheres" Chem. Mater. 2005, 17, 4310-4317. (Materials science, multidisplinary，Ranking: 10/186 = 5.4％, IF:4.818)
  50. Jan, J.-S.; Shantz, D. F.* "Helical Poly-L-Glutamic Acid Templated Nanoporous Aluminum Oxides" Chem. Commun. 2005, 2137-2139.(Chemistry, physical，Ranking: 11/128 = 8.6％, IF:4.426)
  51. Huang, C.-H.*; Young, T.-H.; Lee, Y.-T.; Jan, J.-S.; Cheng C.-K. "Polyethylene Failure in New Jersey Low-Contact Stress Total Knee Arthroplasty" J. Biomedical Mater. Res. 1998, 39, 153-160.
  52. Keh, H.-J.*; Jan, J.-S. "Boundary Effects on Diffusiophoresis and Electrophoresis: Motion of a Colloidal Sphere Normal to a Plane Wall" J. Colloid Interface Sci. 1996, 183, 458-475.

 

Patents

 

1.廖友民、任國光、郭炳林、李桐進、詹正雄，“一種鋰電池檢測方法” 申請案號：102112944，中華民國專利證號I484204，2015。

 

2. 廖友民、游國輝、郭炳林、李桐進、詹正雄”電池組充電方法”中華民國專利 (申請案號：102144149申請日：2013/12/03)

 

3.任國光、傅國盛、郭炳林、李桐進、詹正雄 ”電池健康狀態分析方法”中華民國專利(申請案號：102144151申請日：2013/12/03)

 

4. 詹正雄、顏瀚廷、張瀧元、莊孟澔、周仕凱”連續式廢水純化裝置”中華民國專利(申請案號：102-029BP-TW，證號PK13024，2016)

 

5. 詹正雄、顏瀚廷、張瀧元、莊孟澔、周仕凱”連續式廢水純化裝置”美國專利(申請案號：102-029BAP-US 申請日：2013/02)

 

6. 李勇輪、詹正雄 ”抗反射膜之製備方法”中華民國專利申請案號：104118332，中華民國專利證號I554780，2016。

 

7.傅冠穎、許君漢、郭炳林、詹正雄 ”用於電池的電解質組成物”申請案號：105122985中華民國專利通過，2016。

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